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Dual-Function Nitinol Coronary Stent to Prevent Early Thrombosis and Late Restenosis

Detailed Technology Description

TECHNOLOGYDESCRIPTION:Researchers at the University of Delaware have developed anovel new tool to improve contemporary metal stents used in coronary heart diseasetreatments. The new innovation that they have come up with are dual-functioningnitinol drug-eluting stents. In this structure, a Nano-tubular structure wascreated on the surface of nitinol wires and a coating of dual drugs sirolimusand aspirin were applied to the Nano-tubular surface. This would improve theperformance of the coronary stent. This in turn reduces late-stage restenosis.APPLICATION: This is a potentinnovation in the treatment of coronary artery disease. The innovationfacilitates the revascularization of coronary vessels. PROBLEMS ADDRESSED:Coronary stents have been used in the treatment of coronaryartery disease throughout the past medical history. Many of these stents thatare currently used are made as a bare metal stent. These bare metal stents arenot as promising because they do not have any anti-proliferative agents in themor released by them to prevent hyperplasia and restenosis. Hyperplasia is theenlargement of a tissue caused by the increase in the reproduction rate of thecells. Restenosis is the narrowing of an artery or valve. Metal stents to notprotect against either of these problems. Therefore, the new novel dualfunction nitinol coronary stents which are drug-eluting stents can solve thisproblem.

Countries

United States

Application No.

Patent Pending

Country/Region

USA

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