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One-Step Manufacture Of Nanowire Biosensors

Technology Benefits
One-step in-situ synthesis. Each nanowire is fabricated on the device in seconds and is functionalized as it is grown. There is no need for post-synthesis modification or placement. Easy manufacture. UC's methods are compatible with current fabrication technologies and could be used to develop densely packed arrays of heterogonous probes on an array. Instantaneous, specific, and label-free detection. Biological targets selectively bind to the wire's functional groups, leading to a rapid and easily measured change in conductance. Versatility. The UC methods could be readily adapted to sense biological materials, chemical species, and gases.
Detailed Technology Description
None
Supplementary Information
Patent Number: US8034222B2
Application Number: US2005259557A
Inventor: Myung, Nosang V. | Mulchandani, Ashok | Chen, Wilfred
Priority Date: 26 Oct 2004
Priority Number: US8034222B2
Application Date: 25 Oct 2005
Publication Date: 11 Oct 2011
IPC Current: G01N0027327
US Class: 20440301 | 204400 | 42208202 | 977957
Assignee Applicant: The Regents of the University of California
Title: Conducting polymer nanowire sensors
Usefulness: Conducting polymer nanowire sensors
Summary: The device is useful for detecting an analyte e.g. biotin or its derivative (claimed).
Novelty: Doped conducting polymer material used for detecting analyte comprises analyte-binding species that has different conductivity depending on presence or absence of analyte
Industry
Measurement/Testing
Sub Category
Measurement Tool
Application No.
8034222
Others

Tech ID/UC Case

10283/2004-177-0


Related Cases

2004-177-0

*Abstract

Electrochemical biosensors based on nanotubes or nanowires could be widely used in diagnostic, research, and security applications. However, the problems associated with functionalizing and placing these nano-elements on a device have prevented the practical application of this technology.

University of California scientists have developed a simple one-step methodology for the synthesis of functionalized nanowires that act as biosensors. Nanowires of 100 to 200 nm have been tested that can accurately sense the presence of target biological molecules through changes in conductance when the target binds to the wire's functional ligands

*IP Issue Date
Oct 11, 2011
*Principal Investigator

Name: Wilfred Chen

Department:


Name: Ashok Mulchandani

Department:


Name: Nosang Myung

Department:

Country/Region
USA

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