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Novel Targeted Liposomal Treatment for Tuberculosis

Technology Benefits
Targeted deliverySustained releaseDecreased side effects
Technology Application
mycobacterium infection treatment
Detailed Technology Description
Our inventorΓÇÖs have developed novel anti-TB liposomes that are capable of encapsulating common clinical anti-TB drugs and can be coated with TGF-╬▓1 siRNA. These multifunctional liposomes have proven to be stable under ambient conditions, display low cytotoxicity, and prolonged release in in vitro studies. This nanoparticle system address many of the issues with the current gold standard ofchemotherapeutic treatment and has the potential to significantly improve the treatment of tuberculosis.
*Abstract
Researchers at the University of South Florida have developed novel targetedPEGylated liposomes for co-delivery of siRNA and anti-tubercular drugs for the treatment of mycobacterium infection.
Country/Region
USA

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