WITHACNISTIN Compounds for Treatment of Cancer
- Technology Benefits
- Potent suppressor of STAT3 survival pathway in cancer cellsAnti-tumor activity demonstrated invitro and in-vivo
- Technology Application
- cancer treatment,tumor treatment,tumorigenesis,malignant transformation prevention
- Detailed Technology Description
- Our inventors have discovered that the pharmaceutical composition withacnistin has the ability to suppresshe STAT3 tumor survival pathway and exhibiting potent antitumor activity. Our inventors have also found that growth of cancer cellsin a patient can be inhibited by local/ systemic administration of withacnistin compounds. They have explained methods for modulating STAT3 activity invitro or in vivo by administering the withacnistin compounds.
- *Abstract
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Researchers at the University of South Florida have invented a method for the treatment of tumors and cancerous tissues and for the prevention of tumorigenesis and malignant transformation through the modulation of STAT3 intracellular signaling.
- Country/Region
- USA
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