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Saliva Biomarkers Associated with Glucose Control and Oral Health

Technology Benefits
Obtained from salivaCould be developed as a method to evaluate glucose controlPotential to be a diagnostic for oral health
Technology Application
saliva screening tool to evaluate glycemic control and the potential onset of type 1or type 2 diabetes
Detailed Technology Description
Our inventors have demonstrated a relationship between inflammation, glucose marker HbA1c, and gum health when the saliva of patients with type I Diabetes was analyzed. There is an increase in the presence of molecules of inflammation in the saliva which is significantly associated with the impaired ability to control glucose levels and oral health. The association made could potentially be utilized to develop novel screening methods to evaluate glucose control and onset of type I Diabetes. This could reduce the amount of blood testing that patients currently undergo and make visits to the dentist an important part of routine systemic care. The applications from these findings are of great potential to patients and healthcare providers.
*Abstract
The University of South Florida has investigated the association of salivary inflammation with glycemic control and oral health in Diabetics. They have demonstrated that increased salivary inflammation burden is associated with decreased glycemic control and oral health.
Country/Region
USA

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