Targeted Drug Delivery to Tumor Cells Via Hydrogel
- Technology Benefits
- Slow, extended release of drugSpecific targeting of tumor cellsLow cost
- Technology Application
- drug delivery, tissue engineering, anti-cancer therapeutic
- Detailed Technology Description
- USF inventors have synthesized niosomes embedded in a chitosan hydrogel with encapsulating capabilities of the drug chlorotoxin. The biodegradable chitosan material allows for targeted delivery of the drug while chlorotoxin binds preferentially to tumor cells and not to healthy cells. In addition, specific modifications to the delivery system allows for a fine-tuned release rate while the incorporation into the chitosan hydrogel can prevent the migration of noisome away from tumor sites. This technology will further enhance current drug delivery alternatives for the treatment of cancer and be of great benefit to patients.
- *Abstract
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The University of South Florida has developed a drug delivery system by synthesizing nanoparticle vesicles embedded in a chitosan hydrogel that allows the tumor-targeting drug chlorotoxin to be entrapped internally.
- Country/Region
- USA
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