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One-Step Synthesis of Graphene Quantum Dots

Technology Benefits: Produces small, modisperse size distributionYields GQDs with low cytotoxicity and high biocompatibility for biomedical applicationExcellent solubility in water and many organic solventsInexpensive approach

Technology Application: Bioimaging applications, biomedical applications, optics, electronics, drug delivery, photovoltaic device, light emitting device, biophotonics technology

Detailed Technology Description: Our inventors have designed an inexpensive, quick, and simple approach to synthesize water-soluble GQDs via an oxidation cutting process directly from graphite. This one-step chemical reaction takes as little as 90 minutes to complete with a high yield ofGQDs. These GQDs have an average particle size of between about 1 nanometer (nm) and 20 nm as well as a monodisperse size distribution. Tests with live cells that have been labeled using GQDs have demonstrated their long-term stable capability ofbioimaging application. The novelty of this invention offers a promising therapeutic and diagnostic tool for various diseases, with an emphasis on cancer cell imaging.

*Abstract: USF has developed a fast and facile synthesis route of graphene quantum dots (GQDs) from graphite.

Country/Region: USA

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