Cas9 Mediated Genome Editing Tools for Archaea
- Detailed Technology Description
- Dr. Metcalf from the University of Illinois at Urbana-Champaign has developed a novel method for genome editing in archaea utilizing the Cas9 system.
- Countries
- Not Available
- Application No.
- None
- *Abstract
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Dr. Metcalf from the University of Illinois at Urbana-Champaign has developed a novel method for genome editing in archaea utilizing the Cas9 system. This method utilizes Cas9 machinery with the native archaeal HDR mechanism to edit the genome with no off-target activity. This method can also be combined with archaeal NHEJ machinery to allow random mutagenesis at a location of interest. Notably these tools allow efficient genome editing in methanogenic species potentially leading to novel biogenic strategies for methane production.
For more information, please contact the Office of Technology Management at otm@illinois.edu.
- *IP Issue Date
- None
- *IP Type
- Other Patent
- Country/Region
- USA
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