Anti-recombinant canine thyroid-stimulating hormone (TSH) beta. Line 14H9.E4.A4
- Detailed Technology Description
- Applications Validated for use in IF, ELISA. Recognizes ovine, canine, equine, and feline TSH Beta Thyroid-stimulating hormone (TSH, also known as thyrotropin)is a glycoprotein involved in the control of thyroid structure and metabolism,which stimulates the release of the thyroid hormones. TSH is regulated bythyroid hormone (T3) and various retinoid compounds. TSH binds to thethyroid-stimulating hormone receptor (TSHR), which plays a major role inregulating thyroid function.
- *Abstract
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Reagent Description
Antigen: Thyroid-Stimulating Hormone Beta Subunit(TSH-beta)
Accessionnumber: P54828 (UniProtKB)
Isotype: IgG1k
Clone Name: 14H9.E4.A4(a.k.a. 14H9)
Reactivity: ovine, canine, equine, and feline (possiblyothers)
Immunogen: Recombinant ovine TSH
SpeciesImmunized: Mouse
PurificationMethod: Protein G
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl,0.05% (w/v) Sodium Azide
TestedApplications: ELISA, IF
References
Ferguson DC.Testing for Hypothyroidism in Dogs. VeterinaryClinics of North America: Small Animal Practice 2007;37:647-66
Rayalam S,Eizenstat LD, Davis RR, Hoenig M, Ferguson DC. Expression and purification offeline thyrotropin (fTSH): immunological detection and bioactivity ofheterodimeric and yoked glycoproteins. Domest Anim Endocrinol.2006 Mar;30(3):185-202. Epub 2005 Aug 10.
Ferguson DC:Update on diagnosis of canine hypothyroidism. Vet Clin NorthAm Small Anim Pract 1994, 24(3):515-539
- Country/Region
- USA
