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Pulse Valve for Matrix-Assisted Ionization

Detailed Technology Description

Pulsed Valve Matrix-Assisted Ionization (PV-MAI) is an innovative new ionization approach for matrix-assisted ionization mass spectrometer with high temporal resolution using an electrically actuated pulsed valve. Matrix and analyte samples are deposited on a thin metal foil and placed at the inlet of an ambient ionization mass spectrometer. When the pulsed valve is actuated, a short puff of high pressure gas impinges on the foil and ejects particulate from the sample on the opposite side. Highly charged ions are formed from the particles at the mass spectrometer inlet. Using this source, multiple charged protein ions are produced within a selectable 4 second time window.

Countries

United States

Application No.

Patent Pending

Country/Region

USA

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