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Polyketide Synthase Variants And Uses Thereof


Technology Application

Chemical compound production, gene expression, applications include materials synthesis, antibiotics, immune-suppression, anti-cancer, therapeutic agents, cellulosic ethanol production processes, biofuel enzymes, food enzymes.


Detailed Technology Description

Polyketides are a class of compounds that include antibiotics, immune-suppressants and anticancer agents. Polyketide synthase is a naturally occurring enzyme or engineered enzyme which can be used to prepare commercially useful chemical compounds. Applications of the polyketide synthase variant is applicable in the production of food additives, plasticizers, phytochemicals and phytochemical mixes, etc. Variants of polyketide synthases can have altered capabilities that could expand the enzymatic toolbox for enzyme-based chemical synthesis, and can demonstrate increased enzymatic activity. Efficient methods for production of polyketide synthase variants are needed. he inventors have developed the following: · Efficient methods for production of polyketide synthase variants; · Polyketide synthase variants that have increased activity, stability and solubility;


Others

Tech ID/UC Case

28683/2017-581-0


Related Cases

2017-581-0


Country/Region

USA

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