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Method for rapid high-resolution imaging of large biological samples

Summary

This technology employs a variation of Light Sheet Microscopy called Light Sheet Theta (LS-theta) microscopy to image large biological samples without sacrificing imaging depth or quality.

Technology Benefits

Improved image quality Better imaging depth Accommodates multiple modes of planar imagingDe-synchronized detection allows for greater imaging speedAdaptive correction of parameters allows for high-quality imaging across the entire sampleEliminates limits on lateral dimensions without sacrificing imaging depth and speed

Technology Application

3D imaging of living tissuesImaging of thick slices of human tissues, such as brain slices or other organsImaging of intact brains of large animals, including rat and primateLive imaging for functional activity in mouse brain3D cell culture imagingImaging embryo developmentVolumetric imaging of small organismsOptogenetic applications

Detailed Technology Description

None

Country/Region

USA

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