The Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Technology Application
- Patient assessment and stratification for clinicaltrial
- Detailed Technology Description
- A clinical impairment measure for the upper limb for useafter tetraplegia
- *Abstract
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The GRASSP measure is a) for use by clinicians in theclinical setting as a clinical outcome measure, b) researchersin the clinical/research setting as a primary or secondary outcome measure, andc)academicswho are involved in investigator-driven research. GRASSP development has been a staged processwith a number of different research groups and funding agencies involved.
The GRASSP is a clinical impairment measure for the upperlimb for use after tetraplegia. The measure includes three domains important indescribing hand function: strength, sensibility, and prehension. The overallobjective for the assembly of the GRASSP was to develop a clinical researchtool that could capture information on hand impairment from the cervical(C0-T1) spinal cord injury (SCI) population, obtain integrated sensory andmotor impairment data, and discriminate the population according to the levelof lesion. Specifically, the goal was to design a hand impairment tool that:- Washighly responsive (sensitive) to change over time;
- Couldassess the extent of spontaneous (natural) recovery; and
- Couldbe applicable for use in clinical trials to evaluate the effect of novelinterventions (pharmacological and surgical).
The GRASSP is recommended for use invery early acute phases to approximately one year post tetraplegia. Use of theGRASSP is also recommended when a change in neurological status is beingassessed.
See moredetails at: http://grassptest.com/Default.aspx
- *Principal Investigator
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Dr. Sukhvinder Kalsi-Ryan and Dr. Michael Fehlings, UniversityHealth Network
- *Publications
- Kalsi-Ryan S, Curt A, Verrier MC, Fehlings MG.Development of the Graded Redefined Assessment of Strength, Sensibility andPrehension (GRASSP); Reviewing Measurement Specific to the Upper Limb inTetraplegia. Journal of Neurosurgery Spine, 2012 Sep; 17(1):89-93. PMID: 22985372
- Country/Region
- USA
