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Image-Guided Therapy for Cancer
Detailed Technology Description
Prof.Schultz’s lab at the University of Iowa has developed a novel image guided therapyfor cancer. This invention relates to aclass of molecules, tetra-arylethylene derivatives, that can specificallydeliver drugs to mitochondria in tumor cells. Data demonstrates that this platform can bedesigned to accumulate in the melanoma mitochondrial membranes, disrupt tumorcell metabolism, and induce cell death. Inaddition, this invention allows for imaging the accumulation of the deliveryvehicle molecule in cells, a novel property of lipophilic cations.
Country/Region
USA
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