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Novel Method for Synthesis of Indoles

Detailed Technology Description

Title: Novel Annulation Method for Pharmacological Compound Production Invention: The invention describes a novel method of generating heterocyclic compounds via a 3+2 annulation. This method does not require expensive reagents and, in some instances, can be completed in a chiral manner. Background: Existing methods to synthesize heterocycles usually require multiple steps, metal catalysts, and/or relatively expensive reagents. This invention possesses no such drawbacks and creates heterocycles in a one pot reaction. These heterocyclic compounds can be used to then synthesize a variety of therapeutically relevant compounds. Applications: Anti-HIV compounds Anti-hypertensive compounds AnalgesicsCancer therapeutics Advantages: Cost effective relative to the existing options One pot reaction allows for faster turnaround Generation of chiral compounds Licensing Manager: Laura SilvaLauraS@tla.arizona.edu(520) 626-1557

Country/Region

USA

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