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Proven Mutant Strain for Marek's Disease Vaccine

Detailed Technology Description
Cornell researchers discovered that a mutated strain of Marek’s disease virus (MDV) can be used as an effective vaccine against MDV in poultry.
Others
None
*Abstract

Cornell researchers discovered that a mutated strain of Marek’s disease virus (MDV) can be used as an effective vaccine against MDV in poultry.

  • The mutation disrupts the stability of telomeres by targeting the template region.
  • Vaccination with the mutated strain provided complete protection from MDV, with no disease or tumor development in chickens that were challenged.
  • Vaccination offered 93% protection for animals very susceptible to MDV.
  • Vaccination with the mutated strain was demonstrated to protect against MDV but does not induce MDV or tumors.

Potential Commercial Application:

  • Vaccine for Marek's Disease for poultry.
*Licensing
PhillipOwh607-254-4508po62@cornell.edu
Country/Region
USA

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