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Force-measuring Silicon Microprobe

Detailed Technology Description

A team from Cornell has created, and is developing, a self-advancing microprobe that can measure the stiffness of material it penetrates, for use in reproductive medicine and diagnostics.

Others

Patent: US 8197418
Ramkumar A. et al, "Micro-Dissecting Dual-Probe Testicular Tubule Assay", Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS 2007), pp 1959-1962
Ramkumar A. et al, "Ultrasonic Microprobe Based Tubular Size Assay", IEEE International Ultrasonic Symposium, 28th-31st October, 2007 (in print)

Background on the testicular sperm extraction procedure:

P. N. Schlegel (1999) Testicular sperm extraction: microdissection improves sperm yield with minimal tissue excision. Human Reproduction 14(1) 131-135.

Related publications and patents by Lal and Ramkumar:

Chen, X, et al (2006) Ultrasonically Actuated Silicon Microprobes for Cardiac Signal Recording. IEEE Transactions on Biomedical Engineering 53(8) 1665-71
Son, I., Lal, A. (2002) Remotely Actuated Magnetic Actuator For Microsurgery With Piezoresistive Feedback. Proceedings of the 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine & Biology, Madison, WI.
Chen, X, Lal, A. (2001) Integrated Pressure and Flow Sensor in Silicon-based Ultrasonic Surgical Actuator," IEEE Ultrasonics, Ferroelectrics, and Frequency Control Society Symposium, Atlanta.
Chen, X., Lal, A., (2001) Micromachined Ultrasonic Ophthalmic Microsurgical tool with integrated Pressure sensor. Digest of Technical publications, International Conference on Solid State Sensors and Actuators, Munich.
Son, I. et al (2001) A multifunctional silicon-based microscale surgical system. Sensors and Actuators A. 91(3) 351-356.
Son, I., Lal, A. (2000) Thin-film Composites for Microsurgery. World Conference on Medical Physics and Biomedical Engineering, Chicago.
Lal, A., White, R. M. (1996) Silicon micro-fabricated horns for power ultrasonics. Sensors and Actuators, vol. A54, pp. 542-546.
Amit Lal. (1996) "Micromachined Silicon Ultrasonic Longitudinal Mode Actuators: Theory and Applications to Surgery, Pumping, and Atomization," Ph.D. Dissertation, University of California, Berkeley. pp. 1-175.

Country/Region

USA

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