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Hur-flox/flox Mice

Others

Ghosh M, et al. (2009) Essential role of the RNA-binding protein HuR in progenitor cell survival in mice. J Clin Invest. 119(12):3530-43

*Abstract

Hur-flox mouse for studying the function of RNA binding protein HuR (also known as ELAV1) in specific tissues. This protein regulates the expression of cytokines, chemokines, inflammatory genes, cell growth and apoptotic regulatory genes in many cells and regulates miRNA function.  The mouse may be used as an animal model of inflammation, cancer and apoptosis.

*Licensing
Dan-Oscar Antsonda429@cornell.edu212-746-1297
Country/Region
USA

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