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Integrated Biosensor using Microspheres

Detailed Technology Description
Cornell researchers have developed an on-chip label-free biosensor fabricated with standard lithography techniques.
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*Abstract

The invention relies on unique integrated waveguides that optically trap microspheres in a microfluidic channel. Light transmitted through the waveguide circulates thousands of times around the trapped spheres and these resonances are measured to monitor binding of biomolecules (the microspheres are functionalized such that analytes of interest will bind to them). By observing characteristics such as absorption and refractive index, individual biomolecules can be readily identified. The invention holds great promise in particular for diagnostics where label-free sensing is crucial.

 


                       

Potential Applications

  • Various biosensor applications including diagnostics

                             

Advantages

  • Label-free biosensing
  • On-chip format
  • Uses standard fabrication techniques
*Licensing
Patrick Govangpjg26@cornell.edu(607) 254-2330
Country/Region
USA

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