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Materials and Methods for p11-mediated Gene Therapy of Depression

Detailed Technology Description

This invention providesvectors for increasing p11 expression in a mammal and also provides methods toincrease p11 expression for treating major depressive disorder or refractorydepression or improving responsiveness to treatment for major depressivedisorder or refractory depression.

Others

Reversal of depressed behaviors in mice by p11 genetherapy in the nucleus accumbens. Sci. Transl Med,2010, 2, 54ra76.
Issued US patent: Materials and methods for genemediated therapy of psychiatric disorders. US8642341 B2.

Country/Region

USA

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