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Blocking Leukocyte Migration and Inflammation with Antibodies
Detailed Technology Description
This invention employs antibodies to inhibit the migration of leukocytes in inflammatory processes.
Others
US Patent Nos. 7,223,395 and 8,088,382
CD99 is a key mediator of the transendothelial migration of neutrophils.
J Immunol. 2007 Jan 15;178(2):1136-43.
CD99 plays a major role in the migration of monocytes through endothelial
junctions. Nat Immunol. 2002 Feb;3(2):143-50.
Murine CD99L2 is a cell adhesion molecule involved in the inflammatory response.
Cell Communication & Adhesion 2008 14:227-237
Country/Region
USA
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