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Antidiabetic Effects and Other Health-Related Benefits of Dietary Fatty Acid

Summary
Purdue University researchers have developed a novel dietary fatty acid that has a similar biological effect to TZD. This dietary fatty acid significantly improved symptoms of diabetes in animal models including a 50 to 60 percent decline in plasma insulin, triglycerides, and free fatty acids.
Technology Benefits
Improved treatment of diabetes Insulin independent
Technology Application
Medical/Health Diabetes treatment
Detailed Technology Description
Martha BeluryPurdue Nutrition Science
Countries
United States
Application No.
7,015,249
*Abstract

*Background
Thiazolidinediones (TZDs) are a class of oral insulin-sensitizing agents that improve glucose utilization without stimulating insulin release. The Parke-Davis drug Troglitazone(tm) is an example of a TZD currently being used for treating non-insulin dependent diabetes mellitus (NIDDM or type II diabetes mellitus).
*IP Issue Date
Mar 21, 2006
*IP Type
Utility
*Stage of Development
Concept validated through theory, simulation, or models
*Web Links
Purdue Office of Technology CommercializationPurdueInnovation and EntrepreneurshipMartha BeluryPurdue Nutrition Science
Country/Region
USA

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