Wireless Implantable System To Restore Memory
Stimulation regulated by closed loop feedback system Based on real-time neural recordings High spatial resolutionHigh voltage sensing rangeHighly compact Wireless power and data transfer to/from implantable stimulator (no implanted battery)Low power consumptionWireless data streaming capability to mobile device/computerSimultaneous stimulation and recording capabilityChronically implantable
DBS for: Seizure prevention in epilepsy patientsTreatment of Parkinson’s DiseaseTreatment of chronic depressionRestoring and enhancing memory in epilepsy and TBI patientsSpinal cord neurostimulation for alleviation of chronic pain Functional restoration of impaired sensory systems (e.g. hearing, vision, tactile sensation) Monitoring: Neural monitoring in epilepsy Cardiac rhythm managementBrain-Machine or Brain-Computer Interfaces (BMIs & BCIs) for neural control of prosthetic devices
Researchers have developed a wireless implantable DBS system for patients that delivers electrical brain stimulation. It can function in patients with impaired memory due to TBI to restore and enhance memory. This new technology improves on the DBS electrode design and includes a more compact electronic unit, accomplished with improved data processing algorithms and power optimization strategies.
State Of Development The invention has been prototyped and approved for implantation in humans over 5 years. Background Patients with Traumatic Brain Injury (TBI) represent a large and under-addressed population, with 1.7 million new cases in the US annually. Though deep brain stimulation (DBS) technologies are in common clinical use for Parkinson’s Disease and epilepsy, none have been applied to memory restoration in TBI.New scientific and technological advances have created a basis for applying DBS to TBI. Related Materials Fried, Itzhak, Nanthia Suthana, and Barbara Knowlton. "Specific deep brain stimulation for enhancement of memory." U.S. Patent No. 9,403,010. Additional Technologies by these Inventors Tech ID/UC Case 27286/2014-959-0 Related Cases 2014-959-0
Suthana, Nanthia, et al. "Memory enhancement and deep-brain stimulation of the entorhinal area." New England Journal of Medicine 366.6 (2012): 502-510.
USA
