Methods of Disease Modeling
- Technology Application
- In vitro disease modeling, drug screening.
- Detailed Technology Description
- A UCSD researcher has developed methods to create hydrogels on a chip that mimic normal and pathological properties of tissues dynamically by manipulating the physical environment in which the cells are cultured. In vitro induction of cells into environments with properties that switch from normal to that of a myocardial infarction or breast cancer have been demonstrated.
- Application No.
- 20170328889
- Others
-
Intellectual Property Info
Available for development into commercial applications.
Tech ID/UC Case
24762/2015-040-0
Related Cases
2015-040-0
- *Abstract
-
Identification and evaluation of new therapeutic agents and the identification of suspected disease targets (which typically employ animal models) are expensive, time consuming, etc. In vitro alternatives have relied on the use of conventional cell culture systems which are limited in that they do not allow the three-dimensional interactions that occur between cells and their surrounding tissue. Additionally, cells not only sense and respond to chemical cues, they also respond to the physical environments.
- *IP Issue Date
- Nov 16, 2017
- *Principal Investigator
-
Name: Adam Engler
Department:
- Country/Region
- USA
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