Software for the Identification of Cancer Biomarkers
Software has been designed to function as a pipeline that processes public datasets and information to yield sets of differentially expressed mRNAs, which may be used as biomarkers for specific cancers. The output is also used to design isoform-specific primers for RT-qPCR analysis.
State Of Development Software has been used to identify a potential set of biomarkers, which will be validated. Intellectual Property Info Copyright software available for licensure. Related Materials Roberts A, Pachter L. Streaming fragment assignment for real-time analysis of sequencing experiments. Nat Biotechnol. 2013;10(1): 71-73. Tech ID/UC Case 24481/2015-802-0 Related Cases 2015-802-0
Qu W, al. MFEprimer-2.0: a fast thermodynamics-based program for checking PCR primer specificity. Nucleic Acids Res. 2012, 40: W205–208.
Trapnell C, et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat. Biotechnol. 2010, 28(5): 511-515.
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