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Novel Gene Therapy Solution for Abnormal Fuel Metabolism and Diminished Contractile Function of the Diabetic Heart

Technology Benefits

There are currently no specific approaches available for correcting abnormal fuel flux and improving contractile function of the diabetic heart. Utilizing this novel gene therapy approach, cardiac function could potentially be returned to normal in spite of persistent diabetes in the patient.

Detailed Technology Description

UCSD researchers have discovered a novel gene therapy to correct the abnormal fuel flux in diabetic cardiac myocytes and significantly increase the contractile performance of the heart.

Others

State Of Development

Work in animal models has demonstrated feasibility of the approach, and expression of the transgene in human cardiac muscle cells has been accomplished.

Intellectual Property Info

This technology is available for licensing.

Tech ID/UC Case

24104/2014-256-0

Related Cases

2014-256-0

Country/Region

USA

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