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Novel Bio-Sensor Platform Based on Surface Enhanced Raman Scattering (SERS) Chip

Detailed Technology Description

After several years of research, investigators at UC San Diego’s Jacob’s School of Engineering have developed a portfolio of new technologies to enhance the effectiveness of surface plasmon resonance (SPR) and localized SPR (LSPR) to create sensors capable of identifying single molecules of interest. These sensors have a sensitivity level that is ten orders-of-magnitude greater than commercially available techniques. Included in this body of work are laboratory prototyped nano-hole-array based sensors, including micro-fluidic sample management, illumination optics, single molecule sorting, and novel plasmonic elements capable of sub-diffraction-limit focusing down to 25 nm. The five technology disclosures can be licensed together or separately to realize novel new surface plasmon polariton-based sensors for a variety of applications, including bio-molecule identification.

Supplementary Information

Patent Number: US8094314B2
Application Number: US200891051A
Inventor: Tetz, Kevin | Pang, Lin | Fainman, Yeshaiahu
Priority Date: 21 Oct 2005
Priority Number: US8094314B2
Application Date: 21 Apr 2008
Publication Date: 10 Jan 2012
IPC Current: G01N002155
US Class: 356445
Assignee Applicant: The Regents of the University of California
Title: Optical sensing based on surface plasmon resonances in nanostructures
Usefulness: Optical sensing based on surface plasmon resonances in nanostructures
Summary: Optical sensing device for performing optical sensing of chemical and biological substances.
Novelty: Optical sensing device for performing optical sensing of e.g. chemical substance, has output optical module including output optical polarizer to select light in optical output at selected output polarization for optical detection

Industry

Agriculture

Sub Group

Plant

Application No.

8094314

Others

Related Materials

Published patent application 20080278728.
High-Resolution Surface Plasmon Resonance Sensor Based on Linewidth-Optimized Nanohole Array Transmittance, Optics Letters, Vol. 31, Issue 10, pp. 1528-1530.
Nanoscale Optical Field Localization by Resonantly Focused Plasmons, Optics Express, Vol. 17, Issue 6, pp. 4824-4832.
Plasmonic Sensing of Biological Analytes Through Nanoholes, Sensors Journal, IEEE Volume 8, Issue 12, Dec. 2008 Page(s):2074 - 2079.
Three-Dimensional Composite Metallodielectric Nanostructure for Enhanced Surface Plasmon Resonance Sensing, Appl. Phys. Lett. 94, 073117 (2009); DOI:10.1063/1.3083551.
Cases related to this technology are: SD2006-067, SD2008-090, SD2009-004, SD2009-261, and SD2009-278.

Additional non-public information is available under a confidentiality agreement.

Tech ID/UC Case

19710/2006-067-0

Related Cases

2006-067-0

Country/Region

USA

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