Novel Diagnostic Methods for Citrus Stubborn Disease
- Technology Benefits
- Robust detection - secreted proteins are abundant and stable Rapid, cost-effective processing of large samples Monitors variable distribution of pathogens, and not just at the site of infection Proof-of-concept experiment available in a simple kit
- Technology Application
- Infected trees where pathogens are unevenly distributed Field survey for plants
- Detailed Technology Description
- None
- Application No.
- 9389230
- Others
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Images
Tech ID/UC Case
24526/2012-622-0
Related Cases
2012-622-0
- *Abstract
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Background:
Citrus greening disease, also known as huanglongbing (HLB), is a stubborn bacterial disease caused by insect-transmission and phloem-limited bacterial pathogens. It has been a serious threat to the US citrus industry, decimating many citrus trees and costing the economy $11B in damages annually. The most commonly used method of nucleic-acid based pathogen detection has issues with low-titer (low concentration of antibodies to antigen) and cannot handle the erratic distribution of the pathogens.
Brief Description:
UCR researchers have developed a proof-of-concept for using secreted proteins of bacterial pathogens to detect bacterial diseases. These abundant and stable secreted proteins serve as robust detection markers for immunoassay-based diagnostics. Compared to current methods, this novel method is more high-throughput, economical, and able to monitor the pathogens dispersed throughout the plant transportation system.
- *Applications
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- Infected trees where pathogens are unevenly distributed
- Field survey for plants
- *IP Issue Date
- Jul 12, 2016
- *Principal Investigator
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Name: Wenbo Ma
Department:
Name: Georgios Vidalakis
Department:
- Country/Region
- USA
