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Improvements to Cas9-Mediated Mutation


Technology Benefits

High efficiencyTargeted mutagenesisNo off-targets with dCas9 editing


Technology Application

Precision gene editing in therapeutic contextsIntroduction of desired traits in cropsGeneration of genetically modified organismsIsogenic cell line generation


Detailed Technology Description

None


Others

Publication


Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA


Additional Technologies by these Inventors


Tech ID/UC Case

25181/2016-001-0


Related Cases

2016-001-0


Country/Region

USA

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