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Directional Optical Coherence Tomography Device

Technology Benefits

automated scanning- retains fixation resultincreases optical contrastimages registrationidentifies photoreceptor nuclei

Technology Application

Optical Coherence Tomography retinal layer studyHenle’s fiber layer studiesscreens for pathologiesvisualize diseased tissues

Detailed Technology Description

None

Supplementary Information

Inventor: MAKHIJANI, Vikram | LUJAN, Brandon | ROORDA, Austin | CARROLL, Joseph | RIVERA-CARPIO, Carlos
Priority Number: WO2013123430A1
IPC Current: A61B000310 | A61B000312 | G01B000902
Assignee Applicant: The Regents of the University of California | The Medical College of Wisconsin Inc.
Title: DIRECTIONAL OPTICAL COHERENCE TOMOGRAPHY SYSTEMS AND METHODS | SYSTÈMES ET PROCÉDÉS DE TOMOGRAPHIE PAR COHÉRENCE OPTIQUE DIRECTIONNELLE
Usefulness: DIRECTIONAL OPTICAL COHERENCE TOMOGRAPHY SYSTEMS AND METHODS | SYSTÈMES ET PROCÉDÉS DE TOMOGRAPHIE PAR COHÉRENCE OPTIQUE DIRECTIONNELLE
Summary: Optical coherence tomography system with optical device for imaging internal microstructure of sample e.g. living tissues of eye.
Novelty: Optical coherence tomography system for imaging microstructure of e.g. living tissue of eye, has adjacent mechanism operatively coupled to optically transmissive element of eye, for rotating transmissive element about axes of rotation

Industry

Biomedical

Sub Category

Medical Imaging

Application No.

9427147

Others

Tech ID/UC Case

21850/2012-007-0

Related Cases

2012-007-0

*Abstract

Optical Coherence Tomography provides anatomical structure of ophthalmic tissue based on its reflectance properties as imaged from a single pupil entry position.  This entry position serves as a pivot point for the beam to be scanned back and forth along a single arc.  While current OCT is sufficient to determine the structure of many retinal layers, it does not routinely permit identification of the boundary between the anatomical layer containing the photoreceptor nuclei (outer nuclear layer) and their axons (Henle’s fiber layer).
 
To meet these challenges, investigators at the University of California have developed an directional optical coherence tomography (dOCT) system which introduces an additional element into the path of the OCT beam.  The dOCT system allows the OCT beam position to be steered towards eccentric pupil entry positions.  When this element is rotated about its long axis displacing the beam while maintaining the overall direction of the rays and causes the OCT beam entry position to shift.   Scanning galvos can be used to rapidly rotate this element.   The other changes visible with an dOCT beam entry position changes in normal eyes and in eyes with pathology of clinical importance.

*IP Issue Date

Aug 30, 2016

*Principal Investigator

Name: Joseph Carroll

Department:

Name: Brandon Lujan

Department:

Name: Austin John Roorda

Department:

Name: Carlos Rivera-Carpio

Department:

Name: Vikram Makhijani

Department:

Country/Region

USA