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Monoclonal Antibody To Human Dna Polymerase Epsilon Catalytic Subunit

Technology Benefits
Does not bind to polymerase a, b, or d.
Technology Application
Can be used to specifically recognize the catalytic subunit of polymerase e.
Detailed Technology Description
None
Others

Tech ID/UC Case

18601/1999-013-0


Related Cases

1999-013-0

*Abstract

Human DNA polymerase e contains two apparent subunits of >200 and 55 kDa. Purified polymerase e was used to prepare mouse antiserum capable of recognizing different polymerase e subunits. A mouse monoclonal was identified that had specific recognition for the catalytic subunit of polymerase e (200 kDa).

Reference:
J Biol. Chem. (1995) v270, pp7799-7808.

*Principal Investigator

Name: Stuart Linn

Department:

Country/Region
USA

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