Monoclonal Antibodies Specific For Cyclodiene Insecticides And Related Organochlorine Compounds
- Technology Application
- These monoclonal antibodies are useful for immuno-detection in environmental monitoring and worker exposure applications.
- Detailed Technology Description
- None
- Others
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Tech ID/UC Case
18203/1992-029-0
Related Cases
1992-029-0
- *Abstract
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Investigators at the university of California have identified 4 monoclonal antibodies (Mabs) that can be used to detect and quantify several highly toxic organochlorine compounds at concentrations between 0.01 and 1 ppm. These include the insecticides aldrin, dieldrin, endrin, isodrin, endosulfan, chlordane, heptachlor, and heptachlor epoxide. The antibodies also recognize the technical formulation of toxaphane, the insecticidal gamma isomer of lindane, and endosulfan sulfate, diol, ether and lactone, which are major mammalian urinary metabolites.
Reference:
Karu et al. 1990 Monoclonal Antibody-Based Immunoassay of Cyclodienes. Proceedings, Sixth Annual Waste Testing and Quality Assurance Symposium. July 16-20. Washington, DC pp.I236-50
- *Principal Investigator
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Name: ROBERT CARLSON
Department:
Name: Alexander Karu
Department:
Name: TODD A. SWANSON
Department:
- Country/Region
- USA
