Method For Controlling Cell Adhesion And Growth On Biopolymer Surfaces
- Technology Benefits
- Growth factor control of cells on biopolymer surfaces
- Technology Application
- Cardiovascular implants and polymeric biodevices
- Detailed Technology Description
- None
- Supplementary Information
- Patent Number: US20090130164A1
Application Number: US2007942909A
Inventor: Komvopoulos, Kyriakos | Tajima, Satomi
Priority Date: 20 Nov 2007
Priority Number: US20090130164A1
Application Date: 20 Nov 2007
Publication Date: 21 May 2009
IPC Current: A61K000900 | A61K003500 | C08K000500
US Class: 424423 | 4240931 | 524010 | 524017
Assignee Applicant: The Regents of the University of California
Title: METHOD TO CONTROL CELL ADHESION AND GROWTH ON BIOPOLYMER SURFACES
Usefulness: METHOD TO CONTROL CELL ADHESION AND GROWTH ON BIOPOLYMER SURFACES
Summary: The method is useful to control cell adhesion and growth on biopolymer surfaces.
Novelty: Controlling cell adhesion and growth on biopolymer surfaces, comprises treating polymeric substrate with inert plasma, exposing modified surface to environment having oxygen; and depositing bioentities onto the treated substrate
- Industry
- Biomedical
- Sub Category
- Rehabilitation
- Application No.
- 8927283
- Others
-
Related Technologies
- Method For Grafting Hybrid Crosslinked-uncrosslinked Fluorocarbon Films On Biopolymer Surfaces
- Modification of Polymer Surface with Shielded Plasma
Tech ID/UC Case
17787/2007-063-0
Related Cases
2007-063-0
- *Abstract
-
Endothelial cell seeding is an effective method of preventing thromboembolism on surfaces of cardiovascular implants and devices.
To leverage this effect, researchers at UC Berkeley have investigated the adhesion and cytoskeleton morphology of endothelial cells seeded on low-density polyethylene surfaces. These studies have resulted in the development of a method for controlling cell adhesion and growth on biopolymer surfaces by performing changes in the surface biochemical properties. The novelty of this method relies on the selective use of specific treatment conditions to produce certain surface functionalities that control cell affinity for the polymer surface, followed by adsorption of different proteins for growth factor control
- *IP Issue Date
- Jan 6, 2015
- *Principal Investigator
-
Name: Kyriakos Komvopoulos
Department:
Name: Satomi Tajima
Department:
- Country/Region
- USA
