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Hybridoma Producing Monoclonal Antibodies To Murine Icos

Detailed Technology Description: None

Others: Tech ID/UC Case
17103/2002-008-0

Related Cases
2002-008-0

*Abstract: Investigators at University of California have made a panel of hybridomas producing monoclonal antibodies to the ectodomain of murine ICOS from Syrian hamsters with Chinese hamster ovary cells (CHO) transfected with the murine ICOS gene. Two hybridoma lines were identified; 27A12 (Igm) and 151-9 (IgG).

Ref: Dong, C, Juedes, AE, Temann, UA, Shresta, S, Allison, JP, Ruddle, NH, and Flavell, RA. 2001. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature. 409:97-101

*Principal Investigator: Name: James Allison
Department:

Country/Region: USA

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