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In Planta analysis using solid phase microextraction (SPME) for subsurface contamination delineation

IP Title

ASSEMBLIES FOR USE IN EVALUATING SUBSURFACE CONTAMINATION, AND RELATED METHODS

Detailed Technology Description

None

Supplementary Information

Inventor: Ma, Yinfa
Priority Number: US6576105B1
IPC Current: G01N0027447 | G01N0033574
US Class: 204451
Assignee Applicant: Truman State University,Kirksville
Title: Pteridine analysis by capillary electrophoresis using laser-induced fluorescence detection
Usefulness: Pteridine analysis by capillary electrophoresis using laser-induced fluorescence detection
Summary: For measuring the concentration of pteridines, e.g., 6,7-dimethylpterin, 6-biopterin, D-(⊕)-neopterin, 6-(hydroxymethyl)pterine, pterine, isoxanthopterin, xanthopterin, or pterin-6-carboxylic acid, in a biological sample, e.g., urine sample, for monitoring and screening for cancer in a mammal (Claimed).
Novelty: Measurement of pteridine concentration in sample, e.g., urine for cancer monitoring and screening comprises separating sample through capillary electrophoresis and detecting fluorescence emission from irradiated sample

Industry

Disease Diagnostic/Treatment

Sub Category

Cancer/Tumor

Application Date

May 8, 2009

Application No.

8,286,511

Others

*Abstract

Subsurface contaminant delineation is expensive, time intensive and causes excessive ecological and environmental damage. The in-pianta anaiysis outlined herein allows for rapid analysis for soil and groundwater contaminants in the field to delineate subsurface contamination, particularly with respect to volatile organic compounds (VOCs). Using a variety of analytical techniques, analyses can provide detection in the nanogram/liter range in plant tissues and can also provide accurate quantitative analysis. In-planta sampling can also provide evidence of natural attenuation of contaminants by detecting degradation products. Concentrations in the transpiration streams of plants have been shown to follow a linear relationship to the groundwater, vapor phase or soil concentrations. The availability of trees to sample on a site can also allow for sampling in areas inaccessible to traditional methods of sampling groundwater and soil. Monitoring of sites, including the expansion and contraction of plumes, can also be supported with in-planta analysis, leading to decreased monitoring costs, which are currently targeted by numerous federal agencies and can take the majority of expenses at contaminated sites.

*IP Issue Date

Oct 16, 2012

*IP Publication Date

Nov 12, 2009

*Principal Investigator

Name: Joel Burken, Assoc Professor

Department:

Country/Region

USA