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Probiotic for Heat Stress
Detailed Technology Description
Rats were administered probiotic spores of Bacillus subtilis orally two days before exposure to 45°C (113°F). Body core temperatures reached 40°C (104°F), a temperature that is reached in humans and animals during fever or active exercise. Treatment with the probiotic helped to maintain normal intestinal villi height and mucosal thickness, reduced translocation of bacteria from the gut to circulating blood (measured by LPS and colony counts), reduced breakdown of red blood cells, and maintained normal or reduced levels of cytokines associated with heat stress.
Country/Region
USA
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