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Polymeric Systems for Signal Amplification


Detailed Technology Description

The platform technology enables polymeric nanostructures that are useful for  high level signal amplification, particularly DNAThe systems of the invention comprise polymers and block copolymers, containing a dense arrangement of luminescent molecules that self-assemble into core-shell nanospheres. The polymeric nanospheres contain in the order of 200 polymer chains;  each  incorporates as many as 50 luminescent centers. When an analyte DNA associates with one polymeric nanosphere, it is effectively labeled with approximately 10,000 highly luminescent units.


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USA

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