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Interaction of reelin with very low density lipoprotein (VLDL) receptor for screening and therapies (SJ-98-0045)

*Abstract: This technology is based on the discovery of the interaction between Reelin and the VLDL receptor. It provides a convenient assay system for receptor binding that is adaptable for screening modulators of the interaction between Reelin and the VLDL receptor or similar receptors.
Key words: Reelin, VLDL receptor, Neurodegenerative Diseases
Granted patents or published applications: U.S. Patent No. 6,323,177
Related scientific references: D'Arcangelo G, et al., "Reelin is a ligand for lipoprotein receptors", Neuron 24(2):471-9 (1999).

Country/Region: USA

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