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Methods and composition for diagnosing and preventing a Group B Streptococcal infection (SJ-02-0032)

*Abstract

A novel surface antigen, designated epsilon antigen, on Group B Streptococcus (GBS) encodes a unique serine-rich repeat protein (ssr-2). The epsilon glycoprotein is useful as an immunologic marker for diagnosing GBS infection and in vaccine development. 

Key words: Group B streptococcus, Epsilon antigen, vaccine

Granted patents or published applications: US Patent No. 7,588,773

Related scientific references: Seifert KN, et al; "A unique serine-rich repeat protein (srr) and novel surface antigen (epsilon) associated with a virulent lineage of serotype III Streptococcus agalactiae" Microbiology 152(Pt4):102901040 (2006).

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USA

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