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Mouse model for the development of more effective schizophrenia drugs

Summary

Treatments for schizophrenia are currently lacking, even though it affects 1% of the population globally. This technology is a mouse model of the human ZDHHC8 gene. The deletion of this gene is known to be the leading cause of nonfamilial schizophrenia. Genetic variance in this gene causes a defect in neuron structure and brain function that most commonly manifests as schizophrenia. This technology may provide a route towards effective schizophrenia therapies.

Technology Benefits

Causative genetic association with diseaseClear correlation between molecular mechanism and pathological outcomeTech Ventures Reference: IR CU15276

Technology Application

Drug development for schizophrenia medicationTool to study disease mechanism and pathophysiology

Detailed Technology Description

None

Country/Region

USA

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