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Antibody for targeting cancers characterized by increased iron uptake

Summary: Nicole Suciu-Foca, Ph.D.

Technology Benefits: Relevant to orphan diseases like Adult T Cell Leukemia and Mantle Cell LymphomaSpecifically targets cancer cells over healthy cellsTech Ventures Reference: IR CU14351Patent Information:Patent Pending

Technology Application: Cancer immunophenotyping In vitro sorting (e.g. using flow cytometry) of cells with TfR1 overexpression from healthy cellsTreatment of cancers characterized by TfR1 overexpressionIron replacement in pregnant womenTreatment for neurodegenerative diseases like Alzheimer's and Parkinson's

Detailed Technology Description: Nicole Suciu-Foca, Ph.D.

*Abstract: None

*Inquiry: Sara GusikColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu

*IR: CU14351

*Principal Investigator

*Publications: Tortorella S, Karagiannis TC. "Transferrin receptor-mediated endocytosis: a useful target for cancer therapy" J Membr. Biol. 2014 Feb 27;247(4):291-307.

Country/Region: USA

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