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Antibody for probing the guanine biosynthesis pathway

Summary
Nicole Suciu-Foca, Ph.D.
Technology Benefits
*Role of guanine biosynthesis in cancer and other diseases is not well understood*Specifically targets cells with overexpressed IMPDH2, including tumor cells*Can be used in combination with other antibodiesPatent Information:Patent PendingTech Ventures Reference: IR CU14353
Technology Application
Research into the guanine biosynthesis pathwayFluorescent labeling of tumor cells in which IMPDH2 is upregulatedImmunophenotyping of cells with overexpressed IMPDH2Antibody-drug conjugates for targeting IMPDH2
Detailed Technology Description
Nicole Suciu-Foca, Ph.D.
*Abstract
None
*Inquiry
Sara GusikColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
*IR
CU14353
*Principal Investigator
*Publications
*Chang C-C, Liu Z, Vlad G, Qin H, Qiao X, Mancini DM, Marboe CC, Cortesini R, and Suciu-Foca N. "Ig-Like Transcript 3 Regulates Expression of Proinflammatory Cytokines and Migration of Activated T Cells" Journal of Immunology. 2009;182(9):5208-5216.
Country/Region
USA

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