Low-tech, minimally invasive localized brain drug delivery system
- Summary
- Elisa Konofagou, Ph.D.
- Technology Benefits
- Utilizes intermediate frequencies to minimize damage to non-target regions and ultrasound aberrationsMRI-independent targeting and verificationMore compact than conventional technology allowing portability and increasing patient base to non-specialized clinical settings (e.g., outpatient clinics; community hospitals).Utilizes a single transducer setup, reducing the cost and targeting uncertaintyPatent information:Patent Pending (WO/2011/153268Tech Ventures Reference: IR CU14052
- Technology Application
- Safe and reliable method to open the BBB in specific, shallow, or deep-seated brain regionsSpatially specific neuroscience research in a laboratory settingMay be adapted to improve accessibility and spatial resolution of ultrasound-hemostasis, -lithotripsy, and -assisted thrombolysis.May be adapted for non-invasive research of structures
- Detailed Technology Description
- Elisa Konofagou, Ph.D.
- *Abstract
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None
- *Inquiry
- Satish RaoColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
- *IR
- CU14052
- *Principal Investigator
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- *Publications
- Marquet F, Tung Y, Teichert T, Ferrera VP, Konofagou EE. "Noninvasive, transient and selective blood-brain barrier opening in non-human primates in vivo" PLOS One. 2011 Jul 22;6(7):e22598.
- Country/Region
- USA
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