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Specific mutation in RhoA gene is associated with T-cell lymphoma cancer cells


Summary

Adolfo Ferrando, M.D., Ph.D.


Technology Benefits

Current treatments are primarily chemotherapy combinations with no gene-specific targetsNovel allele associated with T-cell lymphoma provides a new target for drug therapiesHigh levels of Rho are associated with malignant cellsPatent information:Patent Pending


Technology Application

Clinical diagnostic for a patient's risk of T-cell lymphoma and sensitivity to RhoA inhibitorsResearch tool for better understanding of T-cell lymphomaPotential clinical target for new T-cell lymphoma therapies


Detailed Technology Description

Adolfo Ferrando, M.D., Ph.D.


Country/Region

USA

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