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New Human Antibodies for Immuno-histochemical Analysis of Prostate Cancer

Technology Benefits: Using antibodies directed to a protein involved in cancer initiation will allow for better characterization of cancer cells in the early stages of cancer

Technology Application: Immuno-histochemical analysis of prostate carcinomas tissues in humansDetection and characterization of prostate cancer in humans

Detailed Technology Description: Nkx3.1 homeobox gene has restricted expression in the prostate and an essential role in prostate differentiation and function. Loss of function of Nkx3.1 in mice results in prostatic epithelial hyperplasia and dysplasia as a correlate of aging, and N...

*Abstract: None

*Inquiry: Peter GolikovColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu

*IR: 2739

*Principal Investigator

*Publications: Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis. Kim, MJ et al. (2002) PNAS. 99(5): 2884-2889

Country/Region: USA

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