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Total Synthesis of Neurotrophic Factor 11-O-debenzoyltashironin

Summary: Samuel J. Danishefsky, Ph.D..

Technology Benefits: First total synthesisSynthesized from commercially available moleculesNo isolation from plants necessaryPatent information:Patent Issued (US 8067462 B2)Tech Ventures Reference: IR M04-072

Technology Application: Further biological studiesNeutrotrophic activityGrowing neurons from stem cells

Detailed Technology Description: Samuel J. Danishefsky, Ph.D..

*Abstract: None

*Inquiry: Beth KaudererColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu

*IR: M04-072

*Principal Investigator

*Publications: Cook SP, Polara A, Danishefsky SJ. “The Total Synthesis of (+/-)-11-O-Debenzoyltashironin” JACS. 2006;128:16440-16441.

*Web Links: WIPO: WO2006083417

Country/Region: USA

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