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Protein array preparation based on biochemical protein-protein interactions

Summary: Taka-Aki Soto, Ph.D..

Technology Benefits: High throughput drug screening capabilitiesSmall molecule screening can be done under physiological conditions Random protein chips easily made at low-costProtein maintains functionally active conformationMulti-drug screenings done under this platform can be applied to wide array of protein targetsPDZ domain has extremely high binding affinity to SLV, making this assay reliable and consistentPatent information:Patent Pending (WO/2003/076936)Tech Ventures Reference: IR 1218

Technology Application: High-throughput small molecule screening for drug targetsPlatform to make protein chips for novel drug identification

Detailed Technology Description: Taka-Aki Soto, Ph.D..

*Abstract: None

*Inquiry: Jerry KokoshkaColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu

*IR: 1218

*Principal Investigator

*Web Links: Patent number: US20030170723

Country/Region: USA

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