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Therapeutic Agents for Treatment of Myotonic Dystrophy

Detailed Technology Description: None

Countries: Not Available

Application No.: None

*Abstract: Dr. Zimmerman's lab from the University of Illinois has developed a series of bioactive compounds for the treatment of myotonic dystrophy. The compounds disrupt the MBNL-(CUG) foci in vivo and partially rescue the missplicing of cTNT and IR mRNAs.These novel compounds, utilizing bisamidinium-based inhibitors, show a 1000-fold greater inhibition potency than a previous compound and are able to degrade the causative agent of the disease.

*IP Issue Date: None

*IP Type: Other Patent

Country/Region: USA

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