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Deducing Exon Connectivity by RNA-Templated DNA Ligation/Sequencing

Detailed Technology Description: This patented invention discloses a method for studying mRNA sequences without disrupting transcript connectivity or relative abundance. Contrary to existing methods to study mRNA splicing, this metho

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Application No.: None

*Abstract: This patented invention discloses a method for studying mRNA sequences without disrupting transcript connectivity or relative abundance. Contrary to existing methods to study mRNA splicing, this method directly assesses the relative abundance of isoforms, with information regarding multiple ligases and mRNA exon connectivity. Improved understanding of isoforms may facilitate further study of developmental disease or cancer.

*IP Issue Date: None

*IP Type: Other Patent

Country/Region: USA

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