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Luciferin Substrates with Altered Properties

Detailed Technology Description
This technology discloses luciferin amides (e.g., amides derived from firefly luciferin and their analogs) and imaging methods to detect fatty acid amide hydrolase (FAAH) activity in vitro, in live ce
Countries
Not Available
Application No.
None
*Abstract

This technology discloses luciferin amides (e.g., amides derived from firefly luciferin and their analogs) and imaging methods to detect fatty acid amide hydrolase (FAAH) activity in vitro, in live cells, and in vivo. The compounds and methods described are more sensitive and faster than conventional coumarin-based FAAH assays. These assays may be used to identify therapeutic targets for conditions involving inflammation.

*IP Issue Date
None
*IP Type
Other Patent
Country/Region
USA

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